Lumigan is a medication with the active ingredient called bimatoprost. It can also be found under alternative names, including Latisse when used for eyelash growth. Lumigan is primarily used to treat high eye pressure, also known as ocular hypertension, and it can help reduce the risk of glaucoma, a condition that can lead to vision loss if not managed properly.

Lumigan Price Trends

Lumigan pricing spectrum extends from £40.06 to £42.61 for each bottles. The key influencers are pack magnitude and the grade of active substances (1 or 10 ml).

Lumigan Overview

Lumigan, known by its scientific name bimatoprost ophthalmic solution, is a medication primarily prescribed for the management of glaucoma and other conditions that result in increased intraocular pressure. Manufactured by Allergan, its function is to alleviate pressure in the eyes, which, if left unchecked, can lead to optic nerve damage and potential vision loss.

Indications and Uses

Lumigan is indicated for the reduction of elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Furthermore, it serves as a treatment option for those seeking fuller, longer, and darker eyelashes, as it is also approved for hypotrichosis of the eyelashes.

Dosage and Administration

For glaucoma and ocular hypertension, the typical regimen involves one drop in the affected eye(s) once daily in the evening. For eyelash enhancement, a single drop is applied nightly to the skin of the upper eyelid margin at the base of the eyelashes using the accompanying sterile applicators. Precise application is crucial to avoid unwanted hair growth outside of the desired treatment area.

Contraindications and Precautions

Lumigan is contraindicated in patients with a known hypersensitivity to bimatoprost or any other component in the formula. Caution is advised when prescribing to those with active intraocular inflammation as bimatoprost may exacerbate this. Patients with known risk factors for macular edema, including aphakia, pseudophakia, and damaged posterior lens capsule, should also use Lumigan with caution.

Drug Interactions

Concomitant use of Lumigan with other prostaglandin analogs may decrease its efficacy. It is advisable to consult with healthcare providers regarding all other medications being used to determine the potential for interactions.

Adverse Reactions

Patients may encounter side effects including eye redness, growth of eyelashes, itching, and darkening of the iris. If any of these effects persist or worsen, consultation with a healthcare provider is recommended.

Overdose and Emergency Measures

If an overdose occurs, the eye should be flushed with water and medical attention sought. Although there are no specific emergency measures, supportive care and monitoring of vitals may be warranted.

Storage and Handling

Lumigan should be stored at room temperature away from moisture and heat. The bottle must be kept tightly closed when not in use. Properly disposing of any unused or expired product is important for ensuring safety.

Patient Counseling Information

Patients should be instructed on the correct method of application and the importance of adhering to the prescribed regimen. The potential side effects, along with their respective remedial actions, should be clearly communicated.

Clinical Pharmacology

The effectiveness of Lumigan hinges on its ability to target prostaglandin receptors in the eyes, which results in increased outflow of aqueous humor, helping to reduce intraocular pressure.

Clinical Studies

Several studies have supported Lumigan’s efficacy and safety profile. A notable reduction in intraocular pressure has been observed among diverse patient populations, reinforcing its utility in clinical practice.

Mechanism of Action

Lumigan functions as an analog of prostaglandin F2α, specifically targeting the FP receptor, to facilitate the outflow of aqueous fluid from the eye, thus decreasing intraocular pressure.


Following ocular administration, bimatoprost undergoes a rapid bioconversion to its active form. The systemic metabolism mimics that of fatty acids and is primarily excreted via renal pathways.

Nonclinical Toxicology

Extensive nonclinical toxicological evaluations reveal that bimatoprost is well-tolerated, with a low potential for systemic toxicity when administered locally to the eyes.

Carcinogenesis, Mutagenesis, Impairment of Fertility

No evidence suggests that bimatoprost is carcinogenic or mutagenic. Some animal studies showed reversible reproductive effects at high doses, but these are deemed not relevant to human therapeutic use.

Use in Specific Populations

While promotion of its usage within population subsets such as pregnant or lactating women is conducted with caution, there’s a lack of substantial evidence to suggest significant harm. Nonetheless, the benefits should outweigh any potential risks.

Pediatric Use

The safety and effectiveness of Lumigan in pediatric patients have not been fully established; therefore, it should be prescribed to this demographic only when the potential benefits override the risks.

Geriatric Use

Lumigan is utilized with no specific dose adjustment for the geriatric population; however, general caution is exercised due to the increased likelihood of concurrent diseases or other drug therapy.

Gender and Race

No discernible differences in safety or effectiveness attributable to gender or race have been identified, which allows for a broad application of Lumigan across these demographics.

Renal and Hepatic Impairment

Patients with moderate to severe renal impairment or moderate to severe hepatic impairment display no significant alterations in the clearance of bimatoprost, indicating no need for dose adjustments in these populations.

Drug Abuse and Dependence

Bimatoprost is not associated with any potential for drug abuse or physical dependence given its mode of use and the conditions it treats.


The pharmacodynamic profile of Lumigan outlines its potency in decreasing intraocular pressure with lasting effects sustained over a 24-hour period subsequent to administration.

Clinical Efficacy

Real-world utilization and multiple clinical trials signify that Lumigan is efficacious in bringing down high intraocular pressure, which is paramount for preventing optic nerve damage and preserving visual function.

Safety and Tolerability

Lumigan is generally well-tolerated. Adverse effects are mostly local to the application site and are rarely severe enough to necessitate cessation of treatment.

Postmarketing Experience

Following its market introduction, Lumigan’s safety profile has remained consistent with clinical trial findings, with postmarketing surveillance confirming its stability and effectiveness for its indicated uses.

Patient Package Insert

The accompanying package insert provides an exhaustive account of pertinent information relating to Lumigan, ensuring that patients are fully informed about the medication they are receiving.



Active ingredient



1 bottles, 10 bottles, 2 bottles, 3 bottles, 4 bottles, 5 bottles, 6 bottles, 7 bottles, 8 bottles, 9 bottles


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