{"id":2772,"date":"2025-11-11T18:22:53","date_gmt":"2025-11-11T18:22:53","guid":{"rendered":"https:\/\/allesleypharmacy.co.uk\/pharmacy\/?p=2772"},"modified":"2025-11-11T18:22:53","modified_gmt":"2025-11-11T18:22:53","slug":"johnson-johnsons-new-drug-approved-for-severe-depression","status":"publish","type":"post","link":"https:\/\/allesleypharmacy.co.uk\/pharmacy\/johnson-johnsons-new-drug-approved-for-severe-depression\/","title":{"rendered":"Johnson & Johnson’s New Drug Approved for Severe Depression"},"content":{"rendered":"

Johnson & Johnson has received approval from the Food and Drug Administration (FDA<\/a>) to sell its drug Caplyta for treating major depressive disorder, also known as clinical depression. This is a significant step for the company, as they aim to make Caplyta a top-selling drug. Caplyta is already used to treat schizophrenia and bipolar I and II depression, which together affect around 13 million Americans. Clinical depression affects about 22 million Americans, and two-thirds of these patients do not find enough relief<\/a> from current treatments. The FDA’s approval is based on research showing that Caplyta can greatly improve depression symptoms. In one study, 80% of patients responded to the treatment, and 65% achieved remission. Importantly, Caplyta did not cause common side effects like low sexual desire or weight gain, which often lead patients to stop taking antidepressants<\/a>. This approval supports Johnson & Johnson’s recent purchase of Intra-Cellular Therapies, the company that developed Caplyta. The drug was first approved for schizophrenia in late 2019. Despite the challenges of the COVID-19<\/a> pandemic, Intra-Cellular launched Caplyta successfully with the help of TV commercials. After positive results in a late-stage clinical trial for depression in 2024, the company projected that Caplyta could bring in $5 billion annually. This acquisition was one of the largest in the industry this year. For Johnson & Johnson, this expanded use of Caplyta strengthens their lineup of brain-related drugs, including Spravato, a nasal spray form of ketamine used to treat depression. It also helps offset the loss of another experimental drug that did not meet expectations.<\/p>\n","protected":false},"excerpt":{"rendered":"

Johnson & Johnson has received approval from the Food and Drug Administration (FDA) to sell its drug Caplyta for treating […]<\/p>\n","protected":false},"author":0,"featured_media":2773,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"default","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"categories":[543],"tags":[],"class_list":["post-2772","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pharmaceutical-news"],"_links":{"self":[{"href":"https:\/\/allesleypharmacy.co.uk\/pharmacy\/wp-json\/wp\/v2\/posts\/2772","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/allesleypharmacy.co.uk\/pharmacy\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/allesleypharmacy.co.uk\/pharmacy\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/allesleypharmacy.co.uk\/pharmacy\/wp-json\/wp\/v2\/comments?post=2772"}],"version-history":[{"count":1,"href":"https:\/\/allesleypharmacy.co.uk\/pharmacy\/wp-json\/wp\/v2\/posts\/2772\/revisions"}],"predecessor-version":[{"id":2784,"href":"https:\/\/allesleypharmacy.co.uk\/pharmacy\/wp-json\/wp\/v2\/posts\/2772\/revisions\/2784"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/allesleypharmacy.co.uk\/pharmacy\/wp-json\/wp\/v2\/media\/2773"}],"wp:attachment":[{"href":"https:\/\/allesleypharmacy.co.uk\/pharmacy\/wp-json\/wp\/v2\/media?parent=2772"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/allesleypharmacy.co.uk\/pharmacy\/wp-json\/wp\/v2\/categories?post=2772"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/allesleypharmacy.co.uk\/pharmacy\/wp-json\/wp\/v2\/tags?post=2772"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}