New UK Trial Aims to Improve Dementia Diagnosis with Simple Blood Tests

A new study in the UK, called the ‘READ OUT’ trial, is looking into using blood tests to help diagnose dementia earlier and more accurately. This project, led by Professor Vanessa Raymont at the University of Oxford, is part of a bigger effort to include blood tests in the NHS’s dementia diagnosis process. The trial will use the Cognitive Function Test, created by the Food for the Brain Foundation. This test has already been taken by over 200,000 people and helps individuals understand their risk of dementia and what they can do to lower it. The shift towards prevention is important because recent drug trials for treating Alzheimer’s have not been successful and have had serious side effects. Alongside the READ OUT trial, the Foundation is also starting the ‘DRIfT’ study. This study will look at certain nutrients in the blood to predict future dementia risk and track improvements. The test involves a simple finger prick to measure levels of omega-3, vitamin D, B vitamins, blood sugar control, and antioxidants. Patrick Holford, the founder of the charity, explains that these nutrients are crucial for brain health. Professor David Smith, a former Vice Dean at Oxford University, emphasizes the urgent need for prevention strategies. Anyone can join the research. Over 4,000 people have already signed up, with the goal of reaching 10,000 by the end of the year. Participants will take the online Cognitive Function Test twice a year, fill out a lifestyle questionnaire, and provide blood samples using a home test kit. In return, they will receive personalized advice on how to reduce their risk of cognitive decline.